MIME News - Thursday 9 July 2015

If you would like a story added to next month's newsletter please contact Susan Newland at mime-enquiries@monash.edu

$500 000 MIME Seed Fund – Phase 2 Open Now – Call to Researchers

Around 80 excellent proposals have been received from clinician researchers from the Faculty of Medicine, Nursing and Health Sciences in Phase 1 of the MIME Seed fund process. In this first phase clinician researchers in our partner hospitals were invited to outline areas of unmet clinical need that could potentially be addressed by engineering and IT innovation. The proposals received covered a broad range of clinical areas, such as cardiovascular, neuro and mental health, musculoskeletal, surgical training, trauma, cancer and kidney disease. The accepted proposals can be viewed on the MIME website.

Phase 2 is now open – we invite all Monash researchers to peruse the clinical opportunities put forward in Phase 1 to identify how your research expertise could potentially contribute to solving a major clinical need. The range of research expertise needed is also very broad – such as biomaterials, microfluidics, sensors, mechatronics, wearable technologies, image analysis, data mining, industrial design, CFD, biomarkers and bioinformatics, nanotechnology, decision support and app development.

For those topics where you have relevant expertise and are interested in being part of the solution team, please contact the clinician researcher to discuss the area further. Contact details are available on the MIME website. As many of the clinical needs will require a multidisciplinary team to solve the challenge, MIME is able to assist in arranging workshops or brainstorming sessions for potential team members. Please contact MIME's Executive Officer, Susan Newland susan.newland@monash.edu

When your team has formulated a proposed R&D program that addresses the clinical challenge, the lead researcher should submit a Phase 2 application for MIME seed funding. Up to $50 000 may be requested per project area, to deliver a meaningful outcome within 12-18 months. If the area of clinical need has a longer term research challenge that befits a PhD program, teams are invited to flag if they wish to co-supervise a PhD student. 11-12 MIME PhD scholarships are available.

Phase 2 application forms can be downloaded from the MIME website, and must be submitted to Susan Newland, susan.newland@monash.edu by 31 July. Any Monash staff member may submit the application or be part of the team, but the team must include the initiating clinician researcher, and a researcher from either Faculty of Engineering or Faculty of IT. In Phase 2, only submissions directly responding to a clinical opportunity put forward in Phase 1 are eligible for MIME seed funding.

News from the Director - Affinity meetings make their mark

The best way to drive innovation in medical engineering and Med-Tech development  is to get engineers/IT specialists and doctors meeting each other and developing collaborations at an early stage in the evolution of a project or idea. MIME is reaching out to Monash University affiliated clinicians to encourage them to identify problems that require engineering/IT expertise and then present their ideas to a group of Monash Engineers, IT and Art and Design experts (from the Monash Faculty of Art, Design and Architecture (MADA)) at our Affinity Meetings. We have had several of these meetings including a very successful recent Alfred Hospital Affinity meeting where eleven Alfred Hospital Professors gave ‘quick-fire’ presentations over 90 minutes to a group of Monash Engineers and IT Faculty staff who MIME transported to the Alfred for the event. The programme can be viewed on the News and Events webpage of the MIME website. You will see the topics were wide-ranging and have great potential to stimulate the development of new medical technology and IT for diagnostics, monitoring and therapy. We are sure this represents the ‘tip of the iceberg’ in terms of untapped potential or nascent medical engineering-IT projects. A number of engineers, IT and art and design academics now have some new projects and new collaborators to work with. 

MIME aims to hold further Affinity meetings at Monash Health (Monash Medical Centre), Monash School of Psychological Sciences and the Monash University Department of Physiology. We are also keen for our other Monash Clinical Schools to get involved with MIME (Cabrini Health, Eastern Health and Peninsula Health).

MIME is also encouraging these newly established research groups to reach out to industry at an early stage of their projects. MIME has many industry contacts and can facilitate these connections.  

MIME PhD Scholarships

MIME in association with the Monash Health, Alfred Health, the Faculties of Engineering and IT and the Faculty of Medicine have 11 - 12 PhD scholarships for clinically focused, translational projects on offer. The project areas will be selected from our recent call for unmet clinical need, which happened as part of Phase 1 of the MIME seed fund application process. Once project teams have assembled and proposals in Phase 2 have been reviewed, the selected PhD projects will be advertised on the MIME website. A more detailed description of the process is available on our website. We expect that the PhD topic areas on offer will be available towards the end of August 2015. We will be offering a range of elective courses that will provide key training in specific areas of high relevance to the Medical Technologies industry and clinically focused research.

MIME Research Initiatives

MIME has identified a number of clinical themes which research projects are grouped around. Underpinning these themes are a range of capabilities, which in concert with the research programs underway are leading to outputs in key output areas such as medical devices and digital health. Strategically, MIME is undergoing a process where it is affirming the clinical areas we are currently working in and identifying new areas for the future. Some of these emerging themes will come from the recent call for unmet clinical need for investment in projects using the MIME seed fund. This process, along with the imminent formation of a Research Working Group will allow us to roadmap where we are heading and formulate the plan to implement the roadmap.


Monash Uni-Baker IDI-Monash Heart Cardiovascular Alliance meeting

The Monash Uni-Baker IDI-Monash Heart Cardiovascular Alliance meeting was held on Wednesday, 10 June 2015 with broad attendance from Monash Uni, Baker IDI, Alfred Health, Monash Heart and Monash Health. The day highlighted ongoing clinical cardiovascular research as well as identifying unmet clinical need and was aimed at bringing a closer understanding between our physician-scientists and our fundamental/basic scientists and engineers. Speakers gave presentations on hot topics, state of the art for treatment of various diseases, areas of interest, materials and technologies of interest and addressed the big unanswered clinical/research questions and gaps in these areas.

A number of the MIME leadership team and MIME researchers attended the meeting. Prof. John Forsythe spoke on materials for cardiac repair and Prof. Wenlong Cheng spoke about the wearable sensing technologies aimed at cardiac monitoring.

Based on the most significant unmet clinical needs in CVD, a range of research opportunities were identified, and MIME researchers are invited to consider how they may contribute to collaborative projects in these areas. These include:
  1. Designing the ‘perfect device’ for the various valvular structural disorders 
  2. Biomarker for identifying onset of neurotoxicity following cardiac arrest to enable clinical decision making
  3. Biomarkers/identification of vulnerable plaques (as opposed to the already ruptured plaque)
  4. Invitation to follow up on intriguing gene expression findings in the pressure overloaded heart
  5. Innovative approaches for fighting infection/would healing in the very specific problem of line entry/exit in the context of implantation of ventricular assist devices.
  6. Applications for wearable devices which practically become a ‘part’ of the patient’s skin
  7. Applications for access to the ASPREE databases - particularly for prospective studies in the elderly well where the predicted primary endpoints might be particularly insightful:  3787; Deaths:  1422; Dementia:  915; Cancers:  1946; CVD: 1792 (including hospitalisation for cardiac failure); Major haemorrhagic events:   981 
  8. Applications for tissue engineering including light activated disrupted scaffolding bio-organic materials. Discussion on the feasibility of 3-D printed scaffolding.

MIME in the News

This month in MIME in the News, we profile Dr Stephen Wang.

Recently reported in the Age, Monash Institute for Medical Engineering (MIME) researcher Stephen Wang in collaboration with Jenny Keating and Tony Goldschlager have created a potential solution to help people maintain good posture - "the Virtual Spine" project. This smart chair contains pressure sensors that can monitor a person's spine position in real time, compare against their ideal spinal position and wirelessly text message or email feedback to the person in the chair. The project is being carried out in conjunction with Monash Health and Austin Health. The full story can be viewed via the MIME media page.

2015 MIME Travel Grants

The Monash Institute of Medical Engineering (MIME) has a number of travel scholarships available for PhD students, postdoctoral fellows and early career researchers (<5 years post PhD award) working on projects that involve medical technologies. By medical technologies we mean a treatment or device to treat a medical condition, a diagnostic tool or IT system or approach directed towards improvement in clinical outcomes.
This funding, up to $2500, is to cover some of the costs towards:

      i.         International conference attendance in concert with visits to key groups for further learning, career development and to establish networks and collaborations with high profile international research groups, or

    ii.         Travel for new collaborative work or continue existing collaborations with key international research groups.

The travel should be carried out within the next 12 months, i.e. by 31st July 2016. Applications can be submitted electronically via the seed fund tab on the MIME website or via the MIME Travel Grants Google Form. The closing date for applications is 31st August 2015.